CV

Yuzhou Chang

• Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
• Pelotonia Institute for Immuno-Oncology
• Department of Biomedical Informatics, College of Medicine, The Ohio State University

3 Blackfan Circle, Boston, MA
Email: ychang13@bidmc.harvard.edu
GitHub: BMEngineeR

CV download

Education

• Postdoc (01/2024 – Present)
  Joint Postdoctoral Researcher
  • Immuno-Oncology Informatics Group, Pelotonia Institute for Immuno-Oncology, The Ohio State University
  • Beth Israel Deaconess Medical Center, Harvard Medical School
• Ph.D. (08/2018 – 12/2023)
  Biomedical Sciences Graduate Program, The Ohio State University
  • Advisors: Prof. Qin Ma, Prof. Zihai Li
  • Training: Statistical modeling, bioinformatics, computational system biology
• B.E. (09/2012 – 06/2016)
  Biopharmaceutical, China Pharmaceutical University
  • Advisor: Weihua Chu

Honors & Awards

• ICIBM 2023 Student & Trainee Travel Award (07/2023)
• Award for Excellence in Research (Graduate Student) (12/2021)
• Outstanding Student Leader (3 times: 09/2013–09/2015)
• Second-Class Scholarship (09/2015)

Research Interests

• Graph signal processing for spatial transcriptomics.
• Developing computational tools for spatial omics data analysis, including cell-cell communication and tissue architecture identification based on deep learning.
• Applying spatial transcriptomics to immuno-oncology.
• Gene regulatory network inference.

Tool Development

• SpaGFT: Spatial omics feature representation based on Graph Fourier Transform (doc).
• RESEPT: A deep learning framework for tissue architecture identification based on spatial transcriptomics data (GitHub).
• SPRUCE: Bayesian multivariate mixture model for spatial transcriptomics data (GitHub).
• IRIS-FGM: An integrative single-cell RNA-Seq interpretation system for functional module analysis (Bioconductor).
• scGNN: Single-cell Graph Neural Network (GitHub).

For a full list of publications, visit Google Scholar.