SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation

Published in Nature Communications, 2018

Abstract Regulatory T (Treg) cells are essential for maintaining immune homeostasis and tolerance, but the mechanisms regulating the stability and function of Treg cells have not been fully elucidated. Here we show SUMO-specific protease 3 (SENP3) is a pivotal regulator of Treg cells that functions by controlling th…

Recommended citation: Xiaoyan Yu, Yimin Lao, Xiao-Lu Teng, Song Li, Yan Zhou, Feixiang Wang, Xinwei Guo, Siyu Deng, et al.. (2018). "SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation" Nature Communications.
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