Spatially resolved transcriptomics reveals unique gene signatures associated with human temporal cortical architecture and Alzheimer’s pathology
Published in bioRxiv (Cold Spring Harbor Laboratory), 2021
Abstract Alzheimer’s disease (AD) is pathologically characterized by amyloid beta (Aβ) plaques, neurofibrillary tangles (tau aggregates), and alterations in microglia, astrocytes and oligodendrocytes. The mesial temporal lobe is a vulnerable brain region in early AD; however, little is known about the transcriptome-…
Recommended citation: Shuo Chen, Yuzhou Chang, Liangping Li, Diana Acosta, Cody Morrison, Cankun Wang, Dominic Julian, Mark E. Hester, et al.. (2021). "Spatially resolved transcriptomics reveals unique gene signatures associated with human temporal cortical architecture and Alzheimer’s pathology" bioRxiv (Cold Spring Harbor Laboratory).
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