Spatial transcriptomics of human middle temporal gyrus reveals layer‐specific gene expression in early Alzheimer’s disease
Published in Alzheimer s & Dementia, 2021
Background In many neurodegenerative diseases including Alzheimer’s disease (AD), specific subpopulations of cells and brain regions are more sensitive to dysfunction and degeneration than others. For example, excitatory neurons in the layer 2/3 of middle temporal gyrus (MTG) is particularly vulnerable to degenerati…
Recommended citation: Shuo Chen, Yuzhou Chang, Liangping Li, Geidy E. Serrano, Thomas G. Beach, Karen Duff, Qin Ma, Hongjun Fu. (2021). "Spatial transcriptomics of human middle temporal gyrus reveals layer‐specific gene expression in early Alzheimer’s disease" Alzheimer s & Dementia.
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