Ribonucleotide reductase M2 (RRM2): Regulation, function and targeting strategy in human cancer

Published in Genes & Diseases, 2022

Ribonucleotide reductase M2 (RRM2) is a small subunit in ribonucleotide reductases, which participate in nucleotide metabolism and catalyze the conversion of nucleotides to deoxynucleotides, maintaining the dNTP pools for DNA biosynthesis, repair, and replication. RRM2 performs a critical role in the malignant biolo…

Recommended citation: Zanwen Zuo, Zerong Zhou, Yuzhou Chang, Yan Liu, Yuping Shen, Qizhang Li, Lei Zhang. (2022). "Ribonucleotide reductase M2 (RRM2): Regulation, function and targeting strategy in human cancer" Genes & Diseases.
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