Single-cell profiling of murine bladder cancer identifies sex-specific transcriptional signatures with prognostic relevance

Published in iScience, 2023

Bladder cancer (BLCA) is more common in men but more aggressive in women. Sex-based differences in cancer biology are commonly studied using a murine model with BLCA generated by N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN). While tumors in the BBN model have been profiled, these profiles provide limited information…

Recommended citation: Hany Abdel-Hafiz, Saravana Kumar Kailasam Mani, Wesley Huang, Kenneth Gouin, Yuzhou Chang, Tong Xiao, Qin Ma, Zihai Li, et al.. (2023). "Single-cell profiling of murine bladder cancer identifies sex-specific transcriptional signatures with prognostic relevance" iScience.
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