TREM2 mediates MHCII-associated CD4+ T-cell response against gliomas
Published in Neuro-Oncology, 2023
BACKGROUND: Myeloid cells comprise up to 50% of the total tumor mass in glioblastoma (GBM) and have been implicated in promoting tumor progression and immunosuppression. Modulating the response of myeloid cells to the tumor has emerged as a promising new approach for cancer treatment. In this regard, we focus on the…
Recommended citation: Jiaying Zheng, Lingxiao Wang, Shunyi Zhao, Wenjing Zhang, Yuzhou Chang, Dale B. Bosco, Tao Huang, Aastha Dheer, et al.. (2023). "TREM2 mediates MHCII-associated CD4+ T-cell response against gliomas" Neuro-Oncology.
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